Ontology highlight
ABSTRACT:
SUBMITTER: Deloizy C
PROVIDER: S-EPMC5550447 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Deloizy Charlotte C Fossum Even E Barnier-Quer Christophe C Urien Céline C Chrun Tiphany T Duval Audrey A Codjovi Maelle M Bouguyon Edwige E Maisonnasse Pauline P Hervé Pierre-Louis PL Barc Céline C Boulesteix Olivier O Pezant Jérémy J Chevalier Christophe C Collin Nicolas N Dalod Marc M Bogen Bjarne B Bertho Nicolas N Schwartz-Cornil Isabelle I
Scientific reports 20170809 1
XCR1 is selectively expressed on a conventional dendritic cell subset, the cDC1 subset, through phylogenetically distant species. The outcome of antigen-targeting to XCR1 may therefore be similar across species, permitting the translation of results from experimental models to human and veterinary applications. Here we evaluated in pigs the immunogenicity of bivalent protein structures made of XCL1 fused to the external portion of the influenza virus M2 proton pump, which is conserved through st ...[more]