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Pre-stroke apathy symptoms are associated with an increased risk of delirium in stroke patients.

ABSTRACT: Neuropsychiatric symptoms can be interrelated to delirium. We aimed to investigate an association between pre-stroke neuropsychiatric symptoms and the risk of delirium in stroke patients. We included 606 patients (median age: 73, 53% female) with stroke or transient ischemic attack admitted within 48?hours from symptoms onset. We assessed delirium on a daily basis during the first 7 days of hospitalization. To make diagnosis of delirium we used DSM-5 criteria. We used Neuropsychiatric Inventory to assess neuropsychiatric symptoms occurring within 4 weeks prior to stroke. We diagnosed delirium in 28.2% of patients. On univariate analysis, higher score of pre-stroke depression (OR: 1.58, 95% CI: 1.04-2.40, P?=?0.03), apathy (OR: 2.23, 95% CI: 1.44-3.45, P?

SUBMITTER: Klimiec E 

PROVIDER: S-EPMC5550489 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature

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Pre-stroke apathy symptoms are associated with an increased risk of delirium in stroke patients.

Klimiec Elzbieta E   Kowalska Katarzyna K   Pasinska Paulina P   Klimkowicz-Mrowiec Aleksandra A   Szyper Aleksandra A   Pera Joanna J   Slowik Agnieszka A   Dziedzic Tomasz T  

Scientific reports 20170809 1

Neuropsychiatric symptoms can be interrelated to delirium. We aimed to investigate an association between pre-stroke neuropsychiatric symptoms and the risk of delirium in stroke patients. We included 606 patients (median age: 73, 53% female) with stroke or transient ischemic attack admitted within 48 hours from symptoms onset. We assessed delirium on a daily basis during the first 7 days of hospitalization. To make diagnosis of delirium we used DSM-5 criteria. We used Neuropsychiatric Inventory  ...[more]

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