Molecular basis for prostate cancer racial disparities.
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ABSTRACT:
SUBMITTER: Singh SK
PROVIDER: S-EPMC5550772 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Publications
Molecular basis for prostate cancer racial disparities.
Singh Santosh K SK Lillard James W JW Singh Rajesh R
Frontiers in bioscience (Landmark edition) 20170101 3
Prostate cancer (PCa) remains the most common cancer in American men. African-American (AA) men continue to have higher PCa prevalence and mortality rates compared to men in other populations. In addition to socioeconomic factors and lifestyle differences, molecular alterations contribute to this discrepancy. We summarize molecular genetics research results interrelated with the biology of PCa racial disparity. Androgen and androgen receptor (AR) pathways have long been associated with prostate ...[more]
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