Vision Loss after Intravitreal Injection of Autologous "Stem Cells" for AMD.
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ABSTRACT:
SUBMITTER: Kuriyan AE
PROVIDER: S-EPMC5551890 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Vision Loss after Intravitreal Injection of Autologous "Stem Cells" for AMD.
Kuriyan Ajay E AE Albini Thomas A TA Townsend Justin H JH Rodriguez Marianeli M Pandya Hemang K HK Leonard Robert E RE Parrott M Brandon MB Rosenfeld Philip J PJ Flynn Harry W HW Goldberg Jeffrey L JL
The New England journal of medicine 20170301 11
Adipose tissue-derived "stem cells" have been increasingly used by "stem-cell clinics" in the United States and elsewhere to treat a variety of disorders. We evaluated three patients in whom severe bilateral visual loss developed after they received intravitreal injections of autologous adipose tissue-derived "stem cells" at one such clinic in the United States. In these three patients, the last documented visual acuity on the Snellen eye chart before the injection ranged from 20/30 to 20/200. T ...[more]
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Project description:IntroductionIntravitreal injection of therapeutic medications has become one of the most commonly performed procedures in ophthalmology. Over the past decade, a number of guidelines have been published that recommend proper techniques to increase the safety of intravitreal injections. In this course, we teach and practice the skills necessary to perform safe intravitreal injections.MethodsThe course was developed for first-year ophthalmology residents and was designed to be delivered in one 2-hour session. Associated materials include guidelines for faculty facilitators and residents to prepare them for safe intravitreal injection of therapeutic medications. Also included are a slide presentation, wet-lab practice guidelines, and an evaluation form.ResultsLearner response has been universally very positive. Residents (N = 15) have reported that structured lectures with practice in the wet lab improved their skill for intravitreal injection of therapeutic medication.DiscussionOverall, we found that our curriculum improved learner knowledge about safe intravitreal injections and learners' self-assessed confidence in the three objectives of the curriculum.
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2022-10-09 | GSE138719 | GEO