Ontology highlight
ABSTRACT:
SUBMITTER: Davis RS
PROVIDER: S-EPMC55528 | biostudies-literature | 2001 Aug
REPOSITORIES: biostudies-literature
Davis R S RS Wang Y H YH Kubagawa H H Cooper M D MD
Proceedings of the National Academy of Sciences of the United States of America 20010807 17
Investigation of human genome sequences with a consensus sequence derived from receptors for the Fc region of Igs (FcR) led to the identification of a subfamily of five Ig superfamily members that we term the Fc receptor homologs (FcRHs). The closely linked FcRH genes are located in a chromosome 1q21 region in the midst of previously recognized FcR genes. This report focuses on the FcRH1, FcRH2, and FcRH3 members of this gene family. Their cDNAs encode type I transmembrane glycoproteins with 3-6 ...[more]