Ontology highlight
ABSTRACT:
SUBMITTER: Dos Santos JC
PROVIDER: S-EPMC5554156 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Dos Santos Janaina Cardoso JC Grund Lidiane Zito LZ Seibert Carla Simone CS Marques Elineide Eugênio EE Soares Anderson Brito AB Quesniaux Valerie F VF Ryffel Bernhard B Lopes-Ferreira Monica M Lima Carla C
Scientific reports 20170811 1
One of the hallmarks of acute inflammation is neutrophil infiltration of tissues. We investigated molecular mechanisms implicated in acute neutrophilic inflammation induced by the venom of a freshwater stingray (Potamotrygon cf. henlei) in mice. Ray venom induced early mobilization of neutrophil in the microvasculature of cremaster mice and infiltration of the peritoneal cavity 2 hours after injury, in a dose-response manner. IL-1β, IL-6, TNF-α, and KC were produced. The neutrophilic infiltratio ...[more]