Ontology highlight
ABSTRACT:
SUBMITTER: Macianskiene R
PROVIDER: S-EPMC5554165 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Mačianskienė Regina R Almanaitytė Mantė M Treinys Rimantas R Navalinskas Antanas A Benetis Rimantas R Jurevičius Jonas J
Scientific reports 20170811 1
Indocyanine green (ICG) fluorescent dye has been approved by the FDA for use in medical diagnostics. Recently, we demonstrated that ICG dye has voltage-sensitive properties with a dual-component (fast and slow) response in the Langendorff-perfused rabbit heart. Here, we extended our studies by showing the different spectral properties of both components for analysis of the fractional change in ICG fluorescence in response to voltage changes. We used light from four LEDs to obtain excitation; emi ...[more]