Ontology highlight
ABSTRACT:
SUBMITTER: Mikasova L
PROVIDER: S-EPMC5556050 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Mikasova Lenka L Xiong Hui H Kerkhofs Amber A Bouchet Delphine D Krugers Harm J HJ Groc Laurent L
Scientific reports 20170814 1
Stress hormones, such as corticosteroids, modulate the transmission of hippocampal glutamatergic synapses and NMDA receptor (NMDAR)-dependent synaptic plasticity, favouring salient behavioural responses to the environment. The corticosterone-induced synaptic adaptations partly rely on changes in NMDAR signalling, although the cellular pathway underlying this effect remains elusive. Here, we demonstrate, using single molecule imaging and electrophysiological approaches in hippocampal neurons, tha ...[more]