Ontology highlight
ABSTRACT:
SUBMITTER: Said A
PROVIDER: S-EPMC5556661 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Said Abdelrahman A Elmanzalawy Mona M Ma Guanggang G Damiani Armando Mario AM Osterrieder Nikolaus N
Virology journal 20170814 1
Rift Valley fever virus (RVFV) is an arthropod-borne bunyavirus that can cause serious and fatal disease in humans and animals. RVFV is a negative-sense RNA virus of the Phlebovirus genus in the Bunyaviridae family. The main envelope RVFV glycoproteins, Gn and Gc, are encoded on the M segment of RVFV and known inducers of protective immunity. In an attempt to develop a safe and efficacious RVF vaccine, we constructed and tested a vectored equine herpesvirus type 1 (EHV-1) vaccine that expresses ...[more]