Ontology highlight
ABSTRACT:
SUBMITTER: Guo L
PROVIDER: S-EPMC5556695 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Guo Longhua L Zhang Shasha S Rubinstein Boris B Ross Eric E Alvarado Alejandro Sánchez AS
Nature ecology & evolution 20161205 1
Loss of heterozygosity through inbreeding or mitotic errors leads to reductions in progeny survival and fertility. Loss of heterozygosity is particularly exacerbated in geographically isolated populations, which are prone to inbreeding depression and faster rates of extinction. The regenerative capacities of the hermaphroditic biotype of the planarian Schmidtea mediterranea allowed us to perform a systematic genetic test of Mendelian segregation and study the loss of heterozygosity in the Spiral ...[more]