Ontology highlight
ABSTRACT:
SUBMITTER: Fan W
PROVIDER: S-EPMC5558537 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Fan Weimin W Chang Jinjia J Fu Peifeng P
Future medicinal chemistry 20150826 12
Endocrine therapy has become one of most effective forms of targeted adjuvant therapy for hormone-sensitive breast cancer and may be given after surgery or radiotherapy, and also prior, or subsequent to chemotherapy. Current commonly used drugs for adjuvant endocrine therapy can be divided into following three classes: selective estrogen receptor modulators, aromatase inhibitors and selective estrogen receptor downregulators. Tumor cells can develop resistance to endocrine therapy, a major obsta ...[more]