Ontology highlight
ABSTRACT:
SUBMITTER: Ye Q
PROVIDER: S-EPMC5559333 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Metallomics : integrated biometal science 20170801 8
Although manganese (Mn) is critical for the proper functioning of various metabolic enzymes and cofactors, excess Mn in the brain causes neurotoxicity. While the exact transport mechanism of Mn has not been fully understood, several importers and exporters for Mn have been identified over the past decade. In addition to Mn-specific transporters, it has been demonstrated that iron transporters can mediate Mn transport in the brain and peripheral tissues. However, while the expression of iron tran ...[more]