Ontology highlight
ABSTRACT:
SUBMITTER: Chan PHW
PROVIDER: S-EPMC5559586 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Chan Patrick H W PHW Lee Lisa L Kim Erin E Hui Tony T Stoynov Nikolay N Nassar Roy R Moksa Michelle M Cameron Dale M DM Hirst Martin M Gsponer Joerg J Mayor Thibault T
Scientific reports 20170816 1
The yeast Sup35 protein is a subunit of the translation termination factor, and its conversion to the [PSI <sup>+</sup>] prion state leads to more translational read-through. Although extensive studies have been done on [PSI <sup>+</sup>], changes at the proteomic level have not been performed exhaustively. We therefore used a SILAC-based quantitative mass spectrometry approach and identified 4187 proteins from both [psi <sup>-</sup>] and [PSI <sup>+</sup>] strains. Surprisingly, there was very ...[more]