Ontology highlight
ABSTRACT:
SUBMITTER: Song RH
PROVIDER: S-EPMC5559918 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Song Rong-Hua RH Song Rong-Hua RH Li Qian Q Wang Wen W Yao Qiu-Ming QM Shao Xiao-Qing XQ Zhang Jin-An JA
International journal of endocrinology 20170803
As there are no previous studies on the interleukin-22 (IL-22) variants in autoimmune thyroid disease (AITD), the present study aimed to explore the association between polymorphisms of IL-22 and the predisposition to AITD. The study had 975 AITD patients, including 639 Graves' disease (GD) and 336 Hashimoto's thyroiditis (HT) individuals and 851 healthy cohorts. Ligase detection reaction (LDR) and direct sequencing method were used for genotyping the IL-22 gene polymorphisms at rs2046068, rs222 ...[more]