Ontology highlight
ABSTRACT:
SUBMITTER: Mrozek-Wilczkiewicz A
PROVIDER: S-EPMC5559958 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Journal of Cancer 20170705 11
In non-invasive anticancer photodynamic therapy (PDT), a nontoxic photosensitizer (PS), which is activated by visible light, is used as a magic bullet that selectively destroys cancer cells. Recently, we described the combined therapy of 5-aminolevulinic acid (ALA-PDT) with thiosemicarbazone (TSC), i.e. an iron-chelating agent. This resulted in a strong synergistic effect. Herein, we investigated a novel strategy using a combination of PDT consist of the xenobiotic-porphyrin type PS with TSC. We ...[more]