Ontology highlight
ABSTRACT:
SUBMITTER: Zhao N
PROVIDER: S-EPMC5559976 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Zhao Ning N Zhang Guoying G He Minwei M Huang He H Cao Lulu L Yin Ang A Wang Pingzhang P Wang Lu L
Journal of Cancer 20170714 11
<i>SZRD1</i> is a novel gene screened out by high-throughput platform, and so far there exists no systematic function reports. The purpose of our study is to discover the function and mechanism of this novel human gene. Bioinformatics analysis indicates that SZRD1 is a highly conserved intracellular protein. After overexpression of SZRD1, we found that SZRD1 could arrest the cell cycle in G2 phase and play a role in inhibiting cell proliferation and inducing apoptosis. In contrast, after knockdo ...[more]