Asymmetry of the temporal code for space by hippocampal place cells.
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ABSTRACT:
SUBMITTER: Souza BC
PROVIDER: S-EPMC5561149 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Publications
Asymmetry of the temporal code for space by hippocampal place cells.
Souza Bryan C BC Tort Adriano B L ABL
Scientific reports 20170817 1
Hippocampal place cells convey spatial information through spike frequency ("rate coding") and spike timing relative to the theta phase ("temporal coding"). Whether rate and temporal coding are due to independent or related mechanisms has been the subject of wide debate. Here we show that the spike timing of place cells couples to theta phase before major increases in firing rate, anticipating the animal's entrance into the classical, rate-based place field. In contrast, spikes rapidly decouple ...[more]
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