Ontology highlight
ABSTRACT:
SUBMITTER: Speers C
PROVIDER: S-EPMC5562815 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Speers Corey C Zhao Shuang G SG Chandler Ben B Liu Meilan M Wilder-Romans Kari K Olsen Eric E Nyati Shyam S Ritter Cassandra C Alluri Prasanna G PG Kothari Vishal V Hayes Daniel F DF Lawrence Theodore S TS Spratt Daniel E DE Wahl Daniel R DR Pierce Lori J LJ Feng Felix Y FY
NPJ breast cancer 20170818
Increased rates of locoregional recurrence have been observed in triple-negative breast cancer despite chemotherapy and radiation therapy. Thus, approaches that combine therapies for radiosensitization in triple-negative breast cancer are critically needed. We characterized the radiation therapy response of 21 breast cancer cell lines and paired this radiation response data with high-throughput drug screen data to identify androgen receptor as a top target for radiosensitization. Our radiosensit ...[more]