Structural biology of telomerase and its interaction at telomeres.
Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC5564310 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
Structural biology of telomerase and its interaction at telomeres.
Current opinion in structural biology 20170718
Telomerase is an RNP that synthesizes the 3' ends of linear chromosomes and is an important regulator of telomere length. It contains a single long non-coding telomerase RNA (TER), telomerase reverse transcriptase (TERT), and other proteins that vary among organisms. Recent progress in structural biology of telomerase includes reports of the first cryo-electron microscopy structure of telomerase, from Tetrahymena, new crystal structures of TERT domains, telomerase RNA structures and models, and ...[more]
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