Ontology highlight
ABSTRACT:
SUBMITTER: Moss EL
PROVIDER: S-EPMC5565110 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Moss Eli L EL Falconer Shannon B SB Tkachenko Ekaterina E Wang Mingjie M Systrom Hannah H Mahabamunuge Jasmin J Relman David A DA Hohmann Elizabeth L EL Bhatt Ami S AS
PloS one 20170821 8
Immunocompromised individuals are at high risk of developing Clostridium difficile-associated disease (CDAD). Fecal microbiota transplantation (FMT) is a highly effective therapy for refractory or recurrent CDAD and, despite safety concerns, has recently been offered to immunocompromised patients. We investigated the genomics of bacterial composition following FMT in immunocompromised patients over a 1-year period. Metagenomic, strain and gene-level bacterial dynamics were characterized in two C ...[more]