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Road blocks in making platelets for transfusion.

ABSTRACT: The production of laboratory-generated human platelets is necessary to meet present and future transfusion needs. This manuscript will identify and define the major roadblocks that must be overcome to make human platelet production possible for clinical use, and propose solutions necessary to accelerate development of laboratory-generated human platelets to market.

SUBMITTER: Thon JN 

PROVIDER: S-EPMC5565795 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature

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Road blocks in making platelets for transfusion.

Thon J N JN   Medvetz D A DA   Karlsson S M SM   Italiano J E JE  

Journal of thrombosis and haemostasis : JTH 20150601

The production of laboratory-generated human platelets is necessary to meet present and future transfusion needs. This manuscript will identify and define the major roadblocks that must be overcome to make human platelet production possible for clinical use, and propose solutions necessary to accelerate development of laboratory-generated human platelets to market. ...[more]

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