Ontology highlight
ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC5567171 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Zhang Xueyang X Shi Jinping J Ye Xiaohua X Ku Zhiqiang Z Zhang Chao C Liu Qingwei Q Huang Zhong Z
Emerging microbes & infections 20170726 7
Coxsackievirus A16 (CVA16) is one of the major pathogens responsible for hand, foot and mouth disease, which affects more than two million children in the Asian-Pacific region annually. Previous studies have shown that scavenger receptor B2 is a functional receptor for CVA16 that facilitates the uncoating process. However, it remains unclear whether other receptors are required for efficient CVA16 infection. In this study, by using a variety of assays we demonstrated that CVA16 utilizes surface ...[more]