Longitudinal observations of progressive cardiac dysfunction in a cardiomyopathic animal model by self-gated cine imaging based on 11.7-T magnetic resonance imaging.
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ABSTRACT:
SUBMITTER: Saito S
PROVIDER: S-EPMC5567262 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Publications
Longitudinal observations of progressive cardiac dysfunction in a cardiomyopathic animal model by self-gated cine imaging based on 11.7-T magnetic resonance imaging.
Saito Shigeyoshi S Tanoue Minori M Masuda Kasumi K Mori Yuki Y Nakatani Satoshi S Yoshioka Yoshichika Y Murase Kenya K
Scientific reports 20170822 1
The purpose of this study was to longitudinally assess left ventricular function and wall thickness in a hamster model of cardiomyopathy using 11.7-T magnetic resonance imaging (MRI). MRI were performed for six cardiomyopathic J2N-k hamsters and six J2N-n hamsters at 5, 10, 15, and 20 weeks of age. Echocardiography was also performed at 20 weeks. The ejection fraction (EF) at 15 and 20 weeks of age in J2N-k hamsters showed a significant decrease compared with those in controls. Conversely, the e ...[more]
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