Protective Effect of Resveratrol on the Brain in a Rat Model of Epilepsy.
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ABSTRACT:
SUBMITTER: Li Z
PROVIDER: S-EPMC5567521 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Publications
Protective Effect of Resveratrol on the Brain in a Rat Model of Epilepsy.
Li Zhen Z You Zhuyan Z Li Min M Pang Liang L Cheng Juan J Wang Liecheng L
Neuroscience bulletin 20170204 3
Accumulating evidence has suggested resveratrol as a promising drug candidate for the treatment of epilepsy. To validate this, we tested the protective effect of resveratrol on a kainic acid (KA)-induced epilepsy model in rats and investigated the underlying mechanism. We found that acute resveratrol application partially inhibited evoked epileptiform discharges in the hippocampal CA1 region. During acute, silent and chronic phases of epilepsy, the expression of hippocampal kainate glutamate rec ...[more]
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Project description:This SuperSeries is composed of the SubSeries listed below.
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