Ontology highlight
ABSTRACT:
SUBMITTER: Goldman R
PROVIDER: S-EPMC5568017 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Goldman Robert R Loebel Antony A Cucchiaro Josephine J Deng Ling L Findling Robert L RL
Journal of child and adolescent psychopharmacology 20170505 6
<h4>Objective</h4>To evaluate the efficacy and safety of lurasidone in acutely symptomatic adolescent patients with schizophrenia.<h4>Methods</h4>Patients aged 13-17 years were randomly assigned to 6 weeks of double-blind, fixed-dose lurasidone (40 or 80 mg/day) or placebo. Primary and key secondary efficacy measures were change from baseline to week 6 in the Positive and Negative Symptom Scale (PANSS) total score and Clinical Global Impressions-Severity (CGI-S) score, respectively, using mixed ...[more]