Ontology highlight
ABSTRACT:
SUBMITTER: Montembault E
PROVIDER: S-EPMC5569077 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Montembault Emilie E Claverie Marie-Charlotte MC Bouit Lou L Landmann Cedric C Jenkins James J Tsankova Anna A Cabernard Clemens C Royou Anne A
Nature communications 20170823 1
Chromatid segregation must be coordinated with cytokinesis to preserve genomic stability. Here we report that cells clear trailing chromatids from the cleavage site by undergoing two phases of cell elongation. The first phase relies on the assembly of a wide contractile ring. The second phase requires the activity of a pool of myosin that flows from the ring and enriches the nascent daughter cell cortices. This myosin efflux is a novel feature of cytokinesis and its duration is coupled to nuclea ...[more]