Ontology highlight
ABSTRACT:
SUBMITTER: Luo R
PROVIDER: S-EPMC5570013 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Luo Ruibang R Schatz Michael C MC Salzberg Steven L SL
GigaScience 20170701 7
16GT is a variant caller for Illumina whole-genome and whole-exome sequencing data. It uses a new 16-genotype probabilistic model to unify single nucleotide polymorphism and insertion and deletion calling in a single variant calling algorithm. In benchmark comparisons with 5 other widely used variant callers on a modern 36-core server, 16GT demonstrated improved sensitivity in calling single nucleotide polymorphisms, and it provided comparable sensitivity and accuracy for calling insertions and ...[more]