IntaRNA 2.0: enhanced and customizable prediction of RNA-RNA interactions.
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ABSTRACT:
SUBMITTER: Mann M
PROVIDER: S-EPMC5570192 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Publications
IntaRNA 2.0: enhanced and customizable prediction of RNA-RNA interactions.
Mann Martin M Wright Patrick R PR Backofen Rolf R
Nucleic acids research 20170701 W1
The IntaRNA algorithm enables fast and accurate prediction of RNA-RNA hybrids by incorporating seed constraints and interaction site accessibility. Here, we introduce IntaRNAv2, which enables enhanced parameterization as well as fully customizable control over the prediction modes and output formats. Based on up to date benchmark data, the enhanced predictive quality is shown and further improvements due to more restrictive seed constraints are highlighted. The extended web interface provides vi ...[more]
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