Ontology highlight
ABSTRACT:
SUBMITTER: Wang M
PROVIDER: S-EPMC5571541 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Wang Min M Tian Yu Y Du Yu-Yang YY Sun Gui-Bo GB Xu Xu-Dong XD Jiang Hai H Xu Hui-Bo HB Meng Xiang-Bao XB Zhang Jing-Yi JY Ding Shi-Lan SL Zhang Miao-di MD Yang Ming-Hua MH Sun Xiao-Bo XB
Journal of cellular and molecular medicine 20170222 9
The present study was designed to investigate whether Araloside C, one of the major triterpenoid compounds isolated from Aralia elata known to be cardioprotective, can improve heart function following ischaemia/reperfusion (I/R) injury and elucidate its underlying mechanisms. We observed that Araloside C concentration-dependently improved cardiac function and depressed oxidative stress induced by I/R. Similar protection was confirmed in isolated cardiomyocytes characterized by maintaining Ca<sup ...[more]