Ontology highlight
ABSTRACT:
SUBMITTER: Cologna SM
PROVIDER: S-EPMC5571863 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Cologna Stephanie M SM Crutchfield Christopher A CA Searle Brian C BC Blank Paul S PS Toth Cynthia L CL Ely Alexa M AM Picache Jaqueline A JA Backlund Peter S PS Wassif Christopher A CA Porter Forbes D FD Yergey Alfred L AL
Journal of proteome research 20150903 10
Protein quantification, identification, and abundance determination are important aspects of proteome characterization and are crucial in understanding biological mechanisms and human diseases. Different strategies are available to quantify proteins using mass spectrometric detection, and most are performed at the peptide level and include both targeted and untargeted methodologies. Discovery-based or untargeted approaches oftentimes use covalent tagging strategies (i.e., iTRAQ, TMT), where repo ...[more]