Ontology highlight
ABSTRACT:
SUBMITTER: Winther-Larsen A
PROVIDER: S-EPMC5572172 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Winther-Larsen Anne A Demuth Christina C Fledelius Joan J Madsen Anne Tranberg AT Hjorthaug Karin K Meldgaard Peter P Sorensen Boe Sandahl BS
British journal of cancer 20170706 5
<h4>Background</h4>Mutated circulating cell-free DNA (cfDNA) has been suggested as a surrogate marker of tumour burden and aggressiveness of disease. We examined the association between the level of plasma mutant cfDNA and metabolic tumour burden (MTB) measured by <sup>18</sup>F-fluoro-D-glucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET/CT). Furthermore, the presence of mutant cfDNA was correlated with patient survival.<h4>Methods</h4>Forty-six advanced non-small c ...[more]