Ontology highlight
ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC5572334 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Zhang X X Duan J J Kesisoglou F F Novakovic J J Amidon G L GL Jamei M M Lukacova V V Eissing T T Tsakalozou E E Zhao L L Lionberger R R
CPT: pharmacometrics & systems pharmacology 20170711 8
On May 19, 2016, the US Food and Drug Administration (FDA) hosted a public workshop, entitled "Mechanistic Oral Absorption Modeling and Simulation for Formulation Development and Bioequivalence Evaluation." The topic of mechanistic oral absorption modeling, which is one of the major applications of physiologically based pharmacokinetic (PBPK) modeling and simulation, focuses on predicting oral absorption by mechanistically integrating gastrointestinal transit, dissolution, and permeation process ...[more]