Measuring Animal Age with DNA Methylation: From Humans to Wild Animals.
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ABSTRACT:
SUBMITTER: De Paoli-Iseppi R
PROVIDER: S-EPMC5572392 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Measuring Animal Age with DNA Methylation: From Humans to Wild Animals.
De Paoli-Iseppi Ricardo R Deagle Bruce E BE McMahon Clive R CR Hindell Mark A MA Dickinson Joanne L JL Jarman Simon N SN
Frontiers in genetics 20170817
DNA methylation (DNAm) is a key mechanism for regulating gene expression in animals and levels are known to change with age. Recent studies have used DNAm changes as a biomarker to estimate chronological age in humans and these techniques are now also being applied to domestic and wild animals. Animal age is widely used to track ongoing changes in ecosystems, however chronological age information is often unavailable for wild animals. An ability to estimate age would lead to improved monitoring ...[more]
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