Ontology highlight
ABSTRACT:
SUBMITTER: Gottschalk MG
PROVIDER: S-EPMC5573560 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Gottschalk Michael G MG Domschke Katharina K
Dialogues in clinical neuroscience 20170601 2
This review serves as a systematic guide to the genetics of generalized anxiety disorder (GAD) and further focuses on anxiety-relevant endophenotypes, such as pathological worry fear of uncertainty, and neuroticism. We inspect clinical genetic evidence for the familialityl heritability of GAD and cross-disorder phenotypes based on family and twin studies. Recent advances of linkage studies, genome-wide association studies, and candidate gene studies (eg, <i>5-HTT, 5-HT1A, MAOA, BDNF</i>) are out ...[more]