Ontology highlight
ABSTRACT:
SUBMITTER: Terauchi Y
PROVIDER: S-EPMC5573934 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Terauchi Yasuo Y Yamada Yuichiro Y Ishida Hitoshi H Ohsugi Mitsuru M Kitaoka Masafumi M Satoh Jo J Yabe Daisuke D Shihara Nobuyuki N Seino Yutaka Y
Diabetes, obesity & metabolism 20170412 8
The aim of this study was to evaluate the efficacy and safety of sitagliptin administered to elderly patients with type 2 diabetes mellitus (T2DM) for 1 year as compared with glimepiride. Patients aged ≥60 years with T2DM and inadequately controlled blood glucose were randomly assigned to sitagliptin 50 mg once daily or glimepiride 0.5 mg once daily for 52 weeks. The primary efficacy endpoint was the change in glycated haemoglobin (HbA1c) from baseline to week 52. Secondary efficacy endpoints in ...[more]