Ontology highlight
ABSTRACT:
SUBMITTER: Turner JS
PROVIDER: S-EPMC5574538 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Turner Jackson S JS Benet Zachary L ZL Grigorova Irina I
PloS one 20170829 8
Memory B cells are long-lived cells that generate a more vigorous response upon recognition of antigen (Ag) and T cell help than naïve B cells and ensure maintenance of durable humoral immunity. Functionally distinct subsets of murine memory B cells have been identified based on isotype switching of BCRs and surface expression of the co-stimulatory molecule CD80 and co-inhibitory molecule PD-L2. Memory B cells in a subpopulation with low surface expression of CD80 and PD-L2 are predominantly non ...[more]