Ontology highlight
ABSTRACT:
SUBMITTER: Yandrapalli S
PROVIDER: S-EPMC5575222 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Yandrapalli Srikanth S Aronow Wilbert S WS Mondal Pratik P Chabbott David R DR
Archives of medical science : AMS 20170703 5
Heart failure (HF) is one of the leading causes of morbidity, mortality, and health care expenditures in the US and worldwide. For three decades, the pillars of treatment of HF with reduced ejection fraction (HFrEF) were medications that targeted the sympathetic nervous system (SNS) and the renin-angiotensin-aldosterone system (RAAS). Prior attempts to augment the natriuretic peptide system (NPS) for the management of HF failed either due to lack of significant clinical benefit or due to the una ...[more]