Sex moderates the effects of positive and negative affect on clinical pain in patients with knee osteoarthritis.

ABSTRACT:

Background and aims

Sex differences in clinical pain severity and response to experimental pain are commonly reported, with women generally showing greater vulnerability. Affect, including state (a single rating) and stable (average daily ratings over two weeks) positive affect and negative affect has also been found to impact pain sensitivity and severity, and research suggests that affect may modulate pain differentially as a function of sex. The current study aimed to examine sex as a moderator of the relationships between affect and pain-related outcomes among participants with knee osteoarthritis (KOA).

Methods

One hundred and seventy-nine participants (59 men) with KOA completed electronic diaries assessing clinical pain, positive affect, and negative affect. A subset

SUBMITTER: Speed TJ 

PROVIDER: S-EPMC5576503 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature