Ontology highlight
ABSTRACT:
SUBMITTER: Cobb KM
PROVIDER: S-EPMC5576553 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Cobb Kelsey M KM Rabb-Lynch Javon M JM Hoerrner Megan E ME Manders Alex A Zhou Qi Q Watson Mary P MP
Organic letters 20170807 16
Recognizing the importance of all-carbon, quaternary stereocenters in complex molecule synthesis, a stereospecific, nickel-catalyzed cross-coupling of allylic pivalates with arylboroxines to deliver products equipped with quaternary stereocenters and internal alkenes was developed. The enantioenriched allylic pivalate starting materials are readily prepared, and a variety of functional groups can be incorporated on both the allylic pivalate and the arylboroxine. Additional advantages include the ...[more]