Dataset Information

Six-year changes in refraction and related ocular biometric factors in an adult Chinese population.

ABSTRACT:

Purpose

To investigate longitudinal changes in refraction and biometry in Chinese adults.

Design

Population-based prospective cohort study.

Methods

1817 subjects aged ? 35 years were randomly recruited from Yuexiu district, Guangzhou, China in 2008. Of which 1595 (87.8%) were reexamined in 2010 and 1427 (78.5%) were reexamined in 2014. Non-cycloplegic automated refraction and visual acuity test were performed at baseline and the 6-year follow-up examination for all participants. In addition, 50% of the participants were randomly selected for axial length (AL), anterior chamber depth (ACD) and lens thickness (LT) measurements using non-contact partial coherence laser interferometry. Lens power (LP) was calculated with the Bennett's equation.

Results

A total of 1300 participants were included in current analysis (2008 mean [SD] age, 51.4 [10.6] years; 54.5% women). Mean change in spherical equivalence (SE) was +0.24 (95% confidence interval [CI], +0.19 to +0.30), +0.51 (95% CI, +0.46 to +0.57), +0.26 (95% CI, +0.15 to +0.38) and -0.05 (95% CI, -0.21 to +0.10) diopters (D) for individuals in the age groups of 35 to 44, 45 to 54, 55 to 64 and 65+ years at baseline, respectively. Corneal power, AL and LT increased while ACD and LP decreased during the follow-up. Baseline SE and changes in biometric factors could explain 97.2% of the variance in longitudinal SE change while LP solely could explain 65.2%. Six-year mean change in cylinder power was -0.16 (95% CI, -0.19 to -0.13) D, the axis of astigmatism changed from "with-the-rule" to "against-the-rule" in 16.4% of the participants and to "oblique" in 0.9%.

Conclusions

This study confirms a hyperopic shift in the elderly before 65 years old and a myopic shift thereafter. Longitudinal refraction change could be well explained by corresponding biometry changes, especially LP. There is also a shift to "against-the-rule" astigmatism for the adult population.

SUBMITTER: Han X

PROVIDER: S-EPMC5576680 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Six-year changes in refraction and related ocular biometric factors in an adult Chinese population.

Han Xiaotong X Guo Xinxing X Lee Pei Ying PY Morgan Ian G IG He Mingguang M

PloS one 20170830 8

<h4>Purpose</h4>To investigate longitudinal changes in refraction and biometry in Chinese adults.<h4>Design</h4>Population-based prospective cohort study.<h4>Methods</h4>1817 subjects aged ≥ 35 years were randomly recruited from Yuexiu district, Guangzhou, China in 2008. Of which 1595 (87.8%) were reexamined in 2010 and 1427 (78.5%) were reexamined in 2014. Non-cycloplegic automated refraction and visual acuity test were performed at baseline and the 6-year follow-up examination for all particip ...[more]

PMID: 28854269

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Dataset Information

Six-year changes in refraction and related ocular biometric factors in an adult Chinese population.

Purpose

Design

Methods

Results

Conclusions

Publications

Six-year changes in refraction and related ocular biometric factors in an adult Chinese population.

Similar Datasets

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