Ontology highlight
ABSTRACT:
SUBMITTER: Cheung AK
PROVIDER: S-EPMC5576945 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Cheung Alfred K AK Rahman Mahboob M Reboussin David M DM Craven Timothy E TE Greene Tom T Kimmel Paul L PL Cushman William C WC Hawfield Amret T AT Johnson Karen C KC Lewis Cora E CE Oparil Suzanne S Rocco Michael V MV Sink Kaycee M KM Whelton Paul K PK Wright Jackson T JT Basile Jan J Beddhu Srinivasan S Bhatt Udayan U Chang Tara I TI Chertow Glenn M GM Chonchol Michel M Freedman Barry I BI Haley William W Ix Joachim H JH Katz Lois A LA Killeen Anthony A AA Papademetriou Vasilios V Ricardo Ana C AC Servilla Karen K Wall Barry B Wolfgram Dawn D Yee Jerry J
Journal of the American Society of Nephrology : JASN 20170622 9
The appropriate target for BP in patients with CKD and hypertension remains uncertain. We report prespecified subgroup analyses of outcomes in participants with baseline CKD in the Systolic Blood Pressure Intervention Trial. We randomly assigned participants to a systolic BP target of <120 mm Hg (intensive group; <i>n</i>=1330) or <140 mm Hg (standard group; <i>n</i>=1316). After a median follow-up of 3.3 years, the primary composite cardiovascular outcome occurred in 112 intensive group and 131 ...[more]