Ontology highlight
ABSTRACT:
SUBMITTER: Li W
PROVIDER: S-EPMC5577264 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Scientific reports 20170830 1
Chronic cerebral hypoperfusion is a pathological state that is associated with the cognitive impairments in vascular dementia. Oxiracetam is a nootropic drug that is commonly used to treat cognitive deficits of cerebrovascular origins. However, oxiracetam is currently used as a racemic mixture whose effective ingredient has not been identified to date. In this study, we first identified that (S)-oxiracetam, but not (R)-oxiracetam, was the effective ingredient that alleviated the impairments of s ...[more]