Disclosing 3' UTR cis-elements and putative partners involved in gene expression regulation in Leishmania spp.
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ABSTRACT:
SUBMITTER: Terrao MC
PROVIDER: S-EPMC5578504 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Disclosing 3' UTR cis-elements and putative partners involved in gene expression regulation in Leishmania spp.
Terrão Monica Cristina MC Rosas de Vasconcelos Elton José EJ Defina Tânia Aquino TA Myler Peter J PJ Cruz Angela Kaysel AK
PloS one 20170831 8
To identify putative cis-elements involved in gene expression regulation in Leishmania, we previously conducted an in silico investigation to find conserved intercoding sequences (CICS) in the genomes of L. major, L. infantum, and L. braziliensis. Here, the CICS databank was explored to search for sequences that were present in the untranslated regions (UTRs) of groups of genes showing similar expression profiles during in vitro differentiation. Using a selectable marker as a reporter gene, flan ...[more]
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