Ontology highlight
ABSTRACT:
SUBMITTER: Lakatos E
PROVIDER: S-EPMC5579072 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Lakatos Eszter E Stumpf Michael P H MPH
Royal Society open science 20170823 8
Controlling the behaviour of cells by rationally guiding molecular processes is an overarching aim of much of synthetic biology. Molecular processes, however, are notoriously noisy and frequently nonlinear. We present an approach to studying the impact of control measures on motifs of molecular interactions that addresses the problems faced in many biological systems: stochasticity, parameter uncertainty and nonlinearity. We show that our reachability analysis formalism can describe the potentia ...[more]