Ontology highlight
ABSTRACT:
SUBMITTER: Chakhoyan A
PROVIDER: S-EPMC5579277 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Chakhoyan Ararat A Guillamo Jean-Sebastien JS Collet Solène S Kauffmann François F Delcroix Nicolas N Lechapt-Zalcman Emmanuèle E Constans Jean-Marc JM Petit Edwige E MacKenzie Eric T ET Barré Louisa L Bernaudin Myriam M Touzani Omar O Valable Samuel S
Scientific reports 20170831 1
Quantitative imaging modalities for the analysis of hypoxia in brain tumors are lacking. The objective of this study was to generate absolute maps of tissue p<sub>t</sub>O<sub>2</sub> from [<sup>18</sup>F]-FMISO images in glioblastoma and less aggressive glioma patients in order to quantitatively assess tumor hypoxia. An ancillary objective was to compare estimated p<sub>t</sub>O<sub>2</sub> values to other biomarkers: perfusion weighted imaging (PWI) and tumor metabolism obtained from <sup>1</s ...[more]