Ontology highlight
ABSTRACT:
SUBMITTER: He J
PROVIDER: S-EPMC5581032 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
He Jiang J Tang Feiyu F Liu Liyu L Chen Lin L Li Jiang J Ou Danming D Zhang Lu L Li Zhi Z Feng Deyun D Li Wenzheng W Sun Lun-Quan LQ
Oncotarget 20161202 32
The Epstein-Barr virus latent membrane protein 1 (LMP1) is an integral membrane protein. LMP1 has been reported to activate the NF-κB and mitogen-activated protein kinase pathways. However, these effects alone are unable to account for the profound oncogenic properties of LMP1. TAZ is one of the nuclear effectors of Hippo-related pathways and highly expressed in many human tumors. Here, we reported that TAZ was frequently expressed in LMP1-positive nasopharyngeal carcinoma. In NPC cell lines, we ...[more]