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ABSTRACT: Background
Beliefs about medication have been associated with adherence in other diseases but there are no existing disease-specific medication beliefs questionnaires for CF. This mixed-methods validated the Cystic Fibrosis Medication Belief Questionnaire (CF-MBQ), based on social cognitive theory.Methods
Based on previous research, items were developed for five domains: motivation, self-efficacy, perceived importance, and decisional balance to take or miss medications. Cognitive interviews were conducted with 15 adult patients with CF to refine item development. 128 patients with CF completed an online survey and objective medication adherence was measured using pharmacy refill data.Results
The five subscales demonstrated strong psychometric properties, with adequate-to-good internal consistency scores. More importantly, each domain demonstrated construct validity with adherence.Conclusions
These theoretically-derived measures may be important for clinical purposes to provide guidance on appropriate interventions to improve adherence and for research to provide enhanced understanding on patient determinants of medication adherence.
SUBMITTER: Eakin MN
PROVIDER: S-EPMC5581993 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Eakin Michelle N MN Chung Shang-En SE Hoehn Jessica J Borrelli Belinda B Rand-Giovannetti Devin D Riekert Kristin A KA
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20170523 5
<h4>Background</h4>Beliefs about medication have been associated with adherence in other diseases but there are no existing disease-specific medication beliefs questionnaires for CF. This mixed-methods validated the Cystic Fibrosis Medication Belief Questionnaire (CF-MBQ), based on social cognitive theory.<h4>Methods</h4>Based on previous research, items were developed for five domains: motivation, self-efficacy, perceived importance, and decisional balance to take or miss medications. Cognitive ...[more]