Ontology highlight
ABSTRACT:
SUBMITTER: Singh M
PROVIDER: S-EPMC5583182 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Singh Manisha M Kakkar Anupama A Sharma Rinkey R Kharbanda O P OP Monga Nitika N Kumar Manish M Chowdhary Shantanu S Airan Balram B Mohanty Sujata S
Scientific reports 20170904 1
To understand the process of neurogenesis, generation of functional dopaminergic (DAergic) neurons from human mesenchymal stem cells (hMSCs) is important. BDNF has been reported to be responsible for inducing neuronal maturation and functionality. Previously, we have reported the efficient generation of neurons from human bone marrow derived MSCs using FGF2 alone. We hypothesize that hMSCs from various tissues [(bone marrow (BM), adipose tissue (AD) and dental pulp (DP)], if treated with BDNF on ...[more]