Betting on the fastest horse: Using computer simulation to design a combination HIV intervention for future projects in Maharashtra, India.

ABSTRACT:

Objective

To inform the design of a combination intervention strategy targeting HIV-infected unhealthy alcohol users in Maharashtra, India, that could be tested in future randomized control trials.

Methods

Using probabilistic compartmental simulation modeling we compared intervention strategies targeting HIV-infected unhealthy alcohol users on antiretroviral therapy (ART) in Maharashtra, India. We tested interventions targeting four behaviors (unhealthy alcohol consumption, risky sexual behavior, depression and antiretroviral adherence), in three formats (individual, group based, community) and two durations (shorter versus longer). A total of 5,386 possible intervention combinations were tested across the population for a 20-year time horizon and intervention bundles were n

SUBMITTER: Ruggles KV 

PROVIDER: S-EPMC5584966 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature