Dataset Information

Magnetic eye tracking in mice.

ABSTRACT: Eye movements provide insights about a wide range of brain functions, from sensorimotor integration to cognition; hence, the measurement of eye movements is an important tool in neuroscience research. We describe a method, based on magnetic sensing, for measuring eye movements in head-fixed and freely moving mice. A small magnet was surgically implanted on the eye, and changes in the magnet angle as the eye rotated were detected by a magnetic field sensor. Systematic testing demonstrated high resolution measurements of eye position of <0.1°. Magnetic eye tracking offers several advantages over the well-established eye coil and video-oculography methods. Most notably, it provides the first method for reliable, high-resolution measurement of eye movements in freely moving mice, revealing increased eye movements and altered binocular coordination compared to head-fixed mice. Overall, magnetic eye tracking provides a lightweight, inexpensive, easily implemented, and high-resolution method suitable for a wide range of applications.

SUBMITTER: Payne HL

PROVIDER: S-EPMC5584990 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature

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Magnetic eye tracking in mice.

Payne Hannah L HL Raymond Jennifer L JL

eLife 20170905

Eye movements provide insights about a wide range of brain functions, from sensorimotor integration to cognition; hence, the measurement of eye movements is an important tool in neuroscience research. We describe a method, based on magnetic sensing, for measuring eye movements in head-fixed and freely moving mice. A small magnet was surgically implanted on the eye, and changes in the magnet angle as the eye rotated were detected by a magnetic field sensor. Systematic testing demonstrated high re ...[more]

PMID: 28872455

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Project description:BackgroundCriminal associates such as terrorist members are likely to deny knowing members of their network when questioned by police. Eye tracking research suggests that lies about familiar faces can be detected by distinct markers of recognition (e.g. fewer fixations and longer fixation durations) across multiple eye fixation parameters. However, the effect of explicit eye movement strategies to concealed recognition on such markers has not been examined. Our aim was to assess the impact of fixed-sequence eye movement strategies (across the forehead, ears, eyes, nose, mouth and chin) on markers of familiar face recognition. Participants were assigned to one of two groups: a standard guilty group who were simply instructed to conceal knowledge but with no specific instructions on how to do so; and a countermeasures group who were instructed to look at every familiar and unfamiliar face in the same way by executing a consistent sequence of fixations.ResultsIn the standard guilty group, lies about recognition of familiar faces showed longer average fixation durations, a lower proportion of fixations to the inner face regions, and proportionately more viewing of the eyes than honest responses to genuinely unknown faces. In the countermeasures condition, familiar face recognition was detected by longer fixations durations, fewer fixations to the inner regions of the face, and fewer interest areas of the face viewed. Longer fixation durations were a consistent marker of recognition across both conditions for most participants; differences were detectable from the first fixation.ConclusionThe results suggest that individuals can exert a degree of executive control over fixation patterns but that: the eyes are particularly attention-grabbing for familiar faces; the more viewers look around the face, the more they give themselves away; and attempts to deploy the same fixation patterns to familiar and unfamiliar faces were unsuccessful. The results suggest that the best strategy for concealing recognition might be to keep the eyes fixated in the centre of the screen but, even then, recognition is apparent in longer fixation durations. We discuss potential optimal conditions for detecting concealed knowledge of faces.

Dataset Information

Magnetic eye tracking in mice.

Publications

Magnetic eye tracking in mice.

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